Searchable abstracts of presentations at key conferences in endocrinology

ea0094p46 | Endocrine Cancer and Late Effects | SFEBES2023

Utility of recumbent, age-adjusted plasma normetadrenaline thresholds to guide identification of small SDHB-deficient paragangliomas in clinical practice

Anjum Suzana , Gazet Marianne , Hameeduddin Ayshea , Akker Scott , Lim Eugenie

Background: Plasma normetanephrine levels are an annual screening tool for detecting paragangliomas in SDHB mutation carriers. Sensitivity is increased when patients are fasting and recumbent prior to phlebotomy, to allow use of age-adjusted reference ranges rather than the 1180 pmol/l upper limit for ambulatory patients of any age. We present our clinicÂ’s results of samples taken after 30 minutes of recumbency to determine if applying age-adjusted ranges...